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Menopause can be broken down into three stages, though Tang notes that menopause and perimenopause are typically grouped together. Perimenopause: Symptoms like hot flashes and mood swings start as ...
Menopause is the permanent cessation of menstruation resulting from loss of ovarian follicular activity, defined as beginning twelve months after the final natural menstrual cycle. This twelve month time point divides menopause into early and late transition periods known as 'perimenopause' and 'postmenopause'. [4]
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Patients also display involuntary limb movements that occur at periodic intervals anywhere from 20 to 40 seconds apart. They often only last the first half of the night during non-REM sleep stages. Movements do not occur during REM because of muscle atonia. PLMS can be unilateral or bilateral and not really symmetrical or simultaneous. [6]
Perimenstrual breast pain is associated with fibrocystic breast changes. [21] Even without treatment, symptoms tend to decrease in perimenopausal women, [22] and induction of menopause through surgical removal of the ovaries is a treatment of last resort. [17]
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Tibolone, sold under the brand name Livial among others, is a medication which is used in menopausal hormone therapy and in the treatment of postmenopausal osteoporosis and endometriosis. [1] [9] [10] [11] The medication is available alone and is not formulated or used in combination with other medications. [12] It is taken by mouth. [1]
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