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Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and clot-bound factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. [ 28 ]
The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product.
Patient education is a planned interactive learning process designed to support and enable expert patients [1] to manage their life with a disease and/or optimise their health and well-being. [ 2 ] [ 3 ]
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[2] [3] Patients either view online patient education programs and materials in a medical office or from their homes or other remote locations with Internet access. Content may include interactive features such as quizzes, live question and answer sessions (in moderated web seminars), and the ability to complete and submit forms.
Patient Education and Counseling is a monthly peer-reviewed medical journal covering patient education and health communication, especially counseling. It was established in 1979 as Patient Counselling and Health Education , obtaining its current name in 1983.
The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...
An admission note is part of a medical record that documents the patient's status (including history and physical examination findings), reasons why the patient is being admitted for inpatient care to a hospital or other facility, and the initial instructions for that patient's care. [1]