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Cancer is caused by genetic changes leading to uncontrolled cell growth and tumor formation. The basic cause of sporadic (non-familial) cancers is DNA damage and genomic instability . [ 1 ] [ 2 ] A minority of cancers are due to inherited genetic mutations. [ 3 ]
Cancer cells are cells that divide continually, forming solid tumors or flooding the blood or lymph with abnormal cells. Cell division is a normal process used by the body for growth and repair. A parent cell divides to form two daughter cells, and these daughter cells are used to build new tissue or to replace cells that have died because of ...
Cancer is fundamentally a disease of tissue growth regulation. For a normal cell to transform into a cancer cell, the genes that regulate cell growth and differentiation must be altered. [96] The affected genes are divided into two broad categories. Oncogenes are genes that promote cell growth and reproduction.
A neoplasm (/ ˈ n iː oʊ p l æ z əm, ˈ n iː ə-/) [1] [2] is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is ...
Cancers and tumors are caused by a series of mutations. Each mutation alters the behavior of the cell somewhat. Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.
Higher levels of omega-6 fatty acids often found in ultraprocessed foods may interfere with the immune system’s fight against cancer cells, a new study says.
In cancer cells, major changes in gene expression increase glucose uptake to support their rapid growth. Unlike normal cells, which produce lactate only when oxygen is low, cancer cells convert much of the glucose to lactate even in the presence of adequate oxygen. This is known as the “Warburg Effect.”
A new study of colon cancer tumor cells finds the kind of inflammation that is known to be caused by the typical American diet. A new study of colon cancer tumor cells finds the kind of ...