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Alcohol septal ablation was first performed in 1994 by Ulrich Sigwart at the Royal Brompton Hospital in the United Kingdom. [2] Since that time, it has gained favor among physicians and patients due to its minimally invasive nature, thereby avoiding general anesthesia, lengthy inpatient recuperation and other complications associated with open-heart surgery (e.g. septal myectomy).
Septal myectomy is associated with a low perioperative mortality and a high late survival rate. A study at the Mayo Clinic found surgical myectomy performed to relieve outflow obstruction and severe symptoms in HCM was associated with long-term survival equivalent to that of the general population, and superior to obstructive HCM without operation.
When performed properly, an alcohol septal ablation induces a controlled heart attack, in which the portion of the interventricular septum that involves the left ventricular outflow tract is infarcted and will contract into a scar. There is debate over which people are best served by surgical myectomy, alcohol septal ablation, or medical therapy.
This surgery had not been possible prior to 1975 because of difficulty with re-implanting coronary arteries which perfuse the actual heart muscle itself , and even after it was first performed the excellent results from the Mustard operation meant that it was a long time before the Jatene procedure took over.
Srihari S. Naidu is an American physician and Professor of Medicine at New York Medical College who is known for his work on hypertrophic cardiomyopathy including the procedure known as alcohol septal ablation, and for helping to construct the universal diagnostic criteria for cardiogenic shock.
Limit Alcohol: Despite its heart-healthy image, alcohol can raise blood pressure. The AHA recommends limiting alcohol to one drink per day for women and two for men.
Alfred Blalock was an American surgeon most known for his work on the Blue Baby syndrome. [2] C. Rollins Hanlon was also an American surgeon but was best known for his work in cardiology. [3] The procedure that these two men created, known as the Blalock–Hanlon procedure, was a new concept termed atrial septectomy.
Jessica Capshaw and Camilla Luddington talk about their new podcast and reflect on their time on Grey's Anatomy. (Corbis via Getty Images) (Stephane Cardinale - Corbis via Getty Images)