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  2. Bone marrow failure - Wikipedia

    en.wikipedia.org/wiki/Bone_marrow_failure

    Bone marrow failure in both children and adults can be either inherited or acquired. Inherited bone marrow failure is often the cause in young children, while older children and adults may acquire the disease later in life. [3] Acquired bone marrow failure may be due to aplastic anemia [4] or myelodysplastic syndrome.

  3. Myelodysplastic syndrome - Wikipedia

    en.wikipedia.org/wiki/Myelodysplastic_syndrome

    Indicators of a poor prognosis: Advanced age; severe neutropenia or thrombocytopenia; high blast count in the bone marrow (20–29%) or blasts in the blood; Auer rods; absence of ringed sideroblasts; abnormal localization or immature granulocyte precursors in bone marrow section; completely or mostly abnormal karyotypes, or complex marrow ...

  4. Hepatic veno-occlusive disease - Wikipedia

    en.wikipedia.org/wiki/Hepatic_veno-occlusive_disease

    Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant and/or excessive exposure to hepatotoxic pyrrolizidine alkaloids .

  5. Gaucher's disease - Wikipedia

    en.wikipedia.org/wiki/Gaucher's_disease

    Symptoms may begin early in life or in adulthood and mainly affect the liver, spleen, and bone. Enlarged liver and grossly enlarged spleen (together hepatosplenomegaly) are common; [3] the spleen can rupture and cause additional complications. Skeletal weakness and bone disease may be extensive. [3] Spleen enlargement and bone marrow ...

  6. Primary myelofibrosis - Wikipedia

    en.wikipedia.org/wiki/Primary_myelofibrosis

    Signs and symptoms include fever, night sweats, bone pain, fatigue, and abdominal pain. Increased infections, bleeding and an enlarged spleen (splenomegaly) are also hallmarks of the disease. Patients with myelofibrosis have an increased risk of acute meyloid leukemia and frank bone marrow failure.

  7. Mia Hamm's brother died following complications from a bone ...

    www.aol.com/lifestyle/mia-hamms-brother-died...

    The soccer icon is speaking out about GVHD, a serious risk with bone marrow transplants, in order to raise awareness. Mia Hamm's brother died following complications from a bone marrow transplant.

  8. Liver failure - Wikipedia

    en.wikipedia.org/wiki/Liver_failure

    Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1 ] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF ) is increasingly being recognized.

  9. Myelitis - Wikipedia

    en.wikipedia.org/wiki/Myelitis

    Myelitis has an extensive differential diagnosis. The type of onset (acute versus subacute/chronic) along with associated symptoms such as the presence of pain, constitutional symptoms that encompass fever, malaise, weight loss or a cutaneous rash may help identify the cause of myelitis. In order to establish a diagnosis of myelitis, one has to ...

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