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  2. Sulfasalazine - Wikipedia

    en.wikipedia.org/wiki/Sulfasalazine

    Sulfasalazine metabolizes to sulfapyridine. Serum levels should be monitored every three months, and more frequently at the outset. Serum levels above 50 μg/L are associated with side effects. In rare cases, sulfasalazine can cause severe depression in young males. It can also cause oligospermia and temporary infertility.

  3. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors.

  4. Silver sulfadiazine - Wikipedia

    en.wikipedia.org/wiki/Silver_sulfadiazine

    Common side effects include itching and pain at the site of use. [4] Other side effects include low white blood cell levels, allergic reactions, bluish grey discoloration of the skin, red blood cell breakdown, or liver inflammation. [4] Caution should be used in those allergic to other sulfonamides. [4]

  5. Noradrenergic and specific serotonergic antidepressant

    en.wikipedia.org/wiki/Noradrenergic_and_specific...

    In addition, due to their blockade of certain serotonin receptors, serotonergic neurotransmission is not facilitated in unwanted areas, which prevents the incidence of many side effects often associated with selective serotonin reuptake inhibitor (SSRI) antidepressants; [1] [3] hence, in part, the "specific serotonergic" label of NaSSAs. [2]

  6. Disease-modifying antirheumatic drug - Wikipedia

    en.wikipedia.org/wiki/Disease-modifying_anti...

    Combinations of DMARDs are often used, because each drug in the combination can be used in a smaller dose than if it were given alone, thus reducing the risk of side effects. [citation needed] Many patients receive an NSAID and at least one DMARD, sometimes with low-dose oral glucocorticoids. If disease remission is observed, regular NSAIDs or ...

  7. FDA approves opioid-free pain medication with 'no sign of ...

    www.aol.com/fda-approves-opioid-free-pain...

    The new drug is intended for treatment of moderate to severe acute pain in adults. ... The most common side effects of Journavx, according to the company’s website, include itching, muscle ...

  8. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Diabetes medications have four main mechanisms of action: [citation needed] Insulin sensitization: Increased sensitivity of insulin receptors on cells leading to decreased insulin resistance, and higher effects of insulin on blood glucose levels. Stimulation of beta cells: This stimulation increases insulin secretion from beta cells of pancreas.

  9. Thiazolidinedione - Wikipedia

    en.wikipedia.org/wiki/Thiazolidinedione

    Thiazolidinedione ligand dependent transactivation is responsible for the majority of anti-diabetic effects. The activated PPAR/RXR heterodimer binds to peroxisome proliferator hormone response elements upstream of target genes in complex with a number of coactivators such as nuclear receptor coactivator 1 and CREB binding protein, this causes upregulation of genes (for a full list see PPARγ):

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