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  2. List of genetic disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_genetic_disorders

    The following is a list of genetic disorders and if known, type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the parents that causes the impairment to develop within the child. There are over 6,000 known genetic disorders in humans.

  3. ADNP syndrome - Wikipedia

    en.wikipedia.org/wiki/ADNP_syndrome

    The diagnosis of ADNP syndrome is established through genetic testing to identify one or more pathogenic variants on the ADNP gene. Molecular genetic testing in a child with developmental delay or an older individual with intellectual disability typically begins with chromosomal microarray analysis.

  4. Intellectual disability - Wikipedia

    en.wikipedia.org/wiki/Intellectual_disability

    Down syndrome is the most common genetic cause of intellectual disability. Among children, the cause of intellectual disability is unknown for one-third to one-half of cases. [11] About 5% of cases are inherited. [12] Genetic defects that cause intellectual disability, but are not inherited, can be caused by accidents or mutations in genetic ...

  5. Down syndrome - Wikipedia

    en.wikipedia.org/wiki/Down_syndrome

    Down syndrome or Down's syndrome, [12] also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] It is usually associated with developmental delays, mild to moderate intellectual disability, and characteristic physical features.

  6. Severe intellectual disability-progressive spastic diplegia ...

    en.wikipedia.org/wiki/Severe_intellectual...

    Individuals with this condition typically show severe intellectual disability, motor delays, severe speech delay and difficulties, infancy-onset hypotonia affecting the trunk, progressive hypertonia affecting the distal limbs, severe progressive microcephaly, autistic-like symptoms, aggressive behavior towards others and/or oneself, sleep abnormalities, and mild facial dysmorphisms such as a ...

  7. X-linked intellectual disability - Wikipedia

    en.wikipedia.org/wiki/X-linked_intellectual...

    Unlike many other types of intellectual disability, the genetics of these conditions are relatively well understood. [2] [3] It has been estimated there are ~200 genes involved in this syndrome; of these ~100 have been identified. [4] Many of these genes are found on the short 'p' arm of the chromosome, and duplications at Xp11.2 are associated ...

  8. Genetics and abortion - Wikipedia

    en.wikipedia.org/wiki/Genetics_and_abortion

    The genetics and abortion issue is an extension of the abortion debate and the disability rights movement.Since the advent of forms of prenatal diagnosis, such as amniocentesis and ultrasound, it has become possible to detect the presence of congenital disorders in the fetus before birth.

  9. Genetic testing - Wikipedia

    en.wikipedia.org/wiki/Genetic_testing

    Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or through biochemical analysis to measure specific protein output. [1]

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