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Hyperalgesia (/ ˌ h aɪ p ər æ l ˈ dʒ iː z i ə / or /-s i ə /; hyper from Greek ὑπέρ (huper) 'over' + -algesia from Greek ἄλγος (algos) 'pain') is an abnormally increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves and can cause hypersensitivity to stimulus.
Opioid-induced hyperalgesia (OIH) or opioid-induced abnormal pain sensitivity, also called paradoxical hyperalgesia, is an uncommon condition of generalized pain caused by the long-term use of high dosages of opioids [1] such as morphine, [2] oxycodone, [3] and methadone. [4] [5] OIH is not necessarily confined to the original affected site. [6]
Primary hyperalgesia probably relies on a central mechanism. It is argued that MIAs, or C-MiHi primary afferents, are crucial to the initiation of primary hyperalgesia because they have a significant response to capsaicin, which is a chemical commonly used to induce hyperalgesia.
Signs and symptoms of neuropathic pain include allodynia (pain caused by non-painful stimuli), hyperalgesia (an increase in pain perception due to painful stimuli), and paresthesia (abnormal sensations such as needle bites, tingling, itching, and decreased or loss of sensitivity). [17] Chronic visceral cancer pain; Chronic bone cancer pain
Amplified musculoskeletal pain is a syndrome which is a set of characteristic symptoms and signs. Essentially, the syndrome is characterized by diffuse, ongoing, daily pain associated with relatively high levels of incapability and greater care-seeking behavior.
Complex regional pain syndrome (CRPS Type 1 and Type 2), sometimes referred to by the hyponyms Reflex Sympathetic Dystrophy (RSD) or Reflex Neurovascular Dystrophy (RND), is a rare and severe form of neuroinflammatory and dysautonomic disorder causing chronic pain, neurovascular, and neuropathic symptoms.
Hyperesthesia is a condition that involves an abnormal increase in sensitivity to stimuli of the senses.Stimuli of the senses can include sound that one hears, foods that one tastes, textures that one feels, and so forth.
An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and ...