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As a result, blood pools in the blood vessels of the legs for a longer period, and less is returned to the heart, thereby leading to a reduced cardiac output and inadequate blood flow to the brain. Very mild occasional orthostatic hypotension is common and can occur briefly in anyone, although it is prevalent in particular among the elderly and ...
This leads to an occlusion of the artery and thus ischemia. Unlike embolic causes of limb ischemia, thrombosis is progressive and develops over time. In hypercoagulable states, thrombosis can occur in areas without atherosclerosis, and usually presents in patients with malignancy, increased tendency for blood to clot, or low blood flow. [15]
Functional ischemia occurs when the blood flow is normal at rest but insufficient during exercise, presenting clinically as intermittent claudication. Critical ischemia is produced when the reduction in blood flow results in a perfusion deficit at rest and is defined by the presence of pain at rest or trophic lesions in the legs.
The peripheral vascular system is the part of the circulatory system that consists of the veins and arteries not in the chest or abdomen (i.e. in the arms, hands, legs and feet). [1] [2] The peripheral arteries supply oxygenated blood to the body, and the peripheral veins lead deoxygenated blood from the capillaries in the extremities back to ...
Brain ischemia is insufficient blood flow to the brain, and can be acute or chronic. Acute ischemic stroke is a neurological emergency typically caused by a blood clot blocking blood flow in a vessel in the brain. [15] Chronic ischemia of the brain may result in a form of dementia called vascular dementia. [16]
Symptoms of a blood clot in the leg may also be present, such as a red, warm, swollen, and painful leg. [1] Signs of a PE include low blood oxygen levels, rapid breathing, rapid heart rate, and sometimes a mild fever. [11] Severe cases can lead to passing out, abnormally low blood pressure, obstructive shock, and sudden death. [2]
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