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  2. Antacid - Wikipedia

    en.wikipedia.org/wiki/Antacid

    Calcium carbonate antacid tablets. An antacid is a substance which neutralizes stomach acidity and is used to relieve heartburn, indigestion, or an upset stomach. [1] Some antacids have been used in the treatment of constipation and diarrhea. [2] Marketed antacids contain salts of aluminum, calcium, magnesium, or sodium. [2]

  3. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Proton-pump inhibitors have largely superseded the H 2-receptor antagonists, a group of medications with similar effects but a different mode of action, and heavy use of antacids. [3] A potassium-competitive acid blocker (PCAB) revaprazan was marketed in Korea as an alternative to a PPI.

  4. Bismuth subsalicylate - Wikipedia

    en.wikipedia.org/wiki/Bismuth_subsalicylate

    Bismuth subsalicylate is used as an antacid and antidiarrheal, and to treat some other gastrointestinal symptoms, such as nausea. The means by which this occurs is still not well documented. It is thought to be some combination of the following: [4] Stimulation of absorption of fluids and electrolytes by the intestinal wall (antisecretory action)

  5. Mechanism of action - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action

    The mechanism of action of aspirin involves irreversible inhibition of the enzyme cyclooxygenase; [17] therefore suppressing the production of prostaglandins and thromboxanes, thus reducing pain and inflammation. This mechanism of action is specific to aspirin and is not constant for all nonsteroidal anti-inflammatory drugs (NSAIDs). Rather ...

  6. H2 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H2_receptor_antagonist

    Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.

  7. Cimetidine - Wikipedia

    en.wikipedia.org/wiki/Cimetidine

    The mechanism of action of cimetidine as an antacid is as a histamine H 2 receptor antagonist. [30] It has been found to bind to the H 2 receptor with a K d of 42 nM. [ 31 ]

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