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Soursop (also called graviola, guyabano, and in Latin America guanábana) is the fruit of Annona muricata, a broadleaf, flowering, evergreen tree. [4] [5] It is native to the tropical regions of the Americas and the Caribbean and is widely propagated. [5] It is in the same genus, Annona, as cherimoya and is in the Annonaceae family.
Annonacin is a disabling and potentially lethal neurotoxin. [4] [5] [6] Like other acetogenins, it is a mitochondrial complex I (NADH-dehydrogenase) inhibitor. [5]As NADH-dehydrogenase is responsible for the conversion of NADH to NAD+ as well as the establishment of a proton gradient in the mitochondria, annonacin disables the ability of a cell to generate ATP through oxidative phosphorylation ...
There can be many years between promising laboratory work and the availability of an effective anti-cancer drug: Monroe Eliot Wall discovered anti-cancer properties in Camptotheca in 1958, but it was not until 1996 – after further research and rounds of clinical trials – that topotecan, a synthetic derivative of a chemical in the plant, was ...
The acetogenin compounds, which occur in the fruit, seeds, and leaves of many Annonaceae, including soursop (Annona muricata), are neurotoxins and seem to be the cause of a neurodegenerative disease. The disorder is a so-called tauopathy associated with a pathologic accumulation of tau protein in the brain.
Annona glabra is a tropical fruit tree in the family Annonaceae, in the same genus as the soursop and cherimoya.Common names include pond apple, alligator apple (so called because American alligators often eat the fruit), swamp apple, corkwood, bobwood, and monkey apple. [2]
Annona or Anona (from Taíno annon) is a genus of flowering plants in the pawpaw/sugar apple family, Annonaceae.It is the second largest genus in the family after Guatteria, [3] containing approximately 166 [4] species of mostly Neotropical and Afrotropical trees and shrubs.
On Sunday, 179 people were killed as a plane touched down in South Korea, making it the deadliest plane crash in South Korea's history.. Two of the six Jeju Air crew members are the only survivors ...
Homeopathic remedies; ineffective for treating cancer. This is a non-exhaustive list of alternative treatments that have been promoted to treat or prevent cancer in humans but which lack scientific and medical evidence of effectiveness. In many cases, there is scientific evidence that the alleged treatments are not effective, and in some cases ...