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Symptoms of gastrointestinal perforation commonly include severe abdominal pain, nausea, and vomiting. [2] Complications include a painful inflammation of the inner lining of the abdominal wall and sepsis. Perforation may be caused by trauma, bowel obstruction, diverticulitis, stomach ulcers, cancer, or infection. [2]
New ulcers were found in around 87.4 million people worldwide during 2015. [5] About 10% of people develop a peptic ulcer at some point in their life. [10] Peptic ulcers resulted in 267,500 deaths in 2015, down from 327,000 in 1990. [6] [11] The first description of a perforated peptic ulcer was in 1670, in Princess Henrietta of England. [2]
Gene Clark (1944–1991, aged 46) had perforated ulcer and died on May 24, 1991. Doug Hepburn (1926–2000, aged 74) had a perforated ulcer and died on November 22, 2000. Philip Agee (1935–2008, aged 72) had a perforated ulcer and died on January 7, 2008. Barbara Bush (1925–2018, aged 92) was treated for a perforated ulcer in November 2008. [9]
531 Gastric ulcer; 532 Duodenal ulcer; 533 Peptic ulcer, site unspecified; 534 Gastrojejunal ulcer; 535 Gastritis and duodenitis. 535.0 Acute gastritis; 535.6 Duodenitis; 536 Disorders of function of stomach. 536.3 Gastroparesis; 536.8 Dyspepsia; 537 Other disorders of stomach and duodenum; 538 Gastrointestinal mucositis ; 539 Complications of ...
Valentino's syndrome is pain presenting in the right lower quadrant of the abdomen caused by a duodenal ulcer with perforation through the retroperitoneum. [1]It is named after Rudolph Valentino, an Italian actor, who presented with right lower quadrant pain in New York, which turned out to be a perforated peptic ulcer.
Pneumoperitoneum is pneumatosis (abnormal presence of air or other gas) in the peritoneal cavity, a potential space within the abdominal cavity.The most common cause is a perforated abdominal organ, generally from a perforated peptic ulcer, although any part of the bowel may perforate from a benign ulcer, tumor or abdominal trauma.
An erosion is different from an ulcer. An "ulcer" is an area of damage to the gastrointestinal wall (in this case the gastric wall) that extends deeper through the wall than an erosion (an ulcer can extend anywhere from beyond the lamina propria to right through the wall, potentially causing a perforation).
Complications may include shock and acute respiratory distress syndrome. [4] [5] Causes include perforation of the intestinal tract, pancreatitis, pelvic inflammatory disease, stomach ulcer, cirrhosis, a ruptured appendix or even a perforated gallbladder. [3]
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