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The corneal endothelium is a single layer of endothelial cells on the inner surface of the cornea.It faces the chamber formed between the cornea and the iris. The corneal endothelium are specialized, flattened, mitochondria-rich cells that line the posterior surface of the cornea and face the anterior chamber of the eye.
Manual small incision cataract surgery (MSICS) is an evolution of extracapsular cataract extraction (ECCE); the lens is removed from the eye through a self-sealing scleral tunnel wound. A well-constructed scleral tunnel is held closed by internal pressure, is watertight, and does not require suturing.
Cataract surgery and IOL implantation have the safest and highest success rates of any eye care-related procedures. As with any type of surgery, however, some level of risk remains. [7] Most complications of cataract surgery do not result in long-term visual impairment, but some severe complications can lead to irreversible blindness. [90]
Normal endothelial cell count at birth is about 4000 cells/sq mm. Adult population has a count of about 2500 to 2800 cells/Sq mm and loses around 0.6% cells per year. The cells in infant have potential regenerating capacity unlike the adult cell and this can be utilized for PDEK to obtain excellent functional outcome.
Endothelial cells in the cornea are reduced as a result of eye surgery and aging. If the cells die too quickly, a cloudy cornea and vision loss may result. Your retina may detach from its normal position as a result of eye surgery. It’s a rare complication that necessitates immediate medical attention. This is another unusual side effect.
Bullous keratopathy, also known as pseudophakic bullous keratopathy (PBK), is a pathological condition in which small vesicles, or bullae, are formed in the cornea due to endothelial dysfunction. In a healthy cornea, endothelial cells keeps the tissue from excess fluid absorption, pumping it back into the aqueous humor.
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