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Vogt was a pioneer of specular microscopy; around 1913 he used a slit lamp together with a corneal microscope to investigate the structures of the anterior areas of the eye, [3] [5] and in 1918 he was the first to perform direct examination of the corneal endothelium. [6]
Hexagonal cells of corneal endothelium visualized by specular microscopy. The principal physiological function of the corneal endothelium is to allow leakage of solutes and nutrients from the aqueous humor to the more superficial layers of the cornea while at the same time pumping water in the opposite direction, from the stroma to the aqueous.
David Myer Maurice (3 April 1922 in London – 20 July 2002 in Manhattan) was a British ophthalmologist, noted for his contributions to the development of the specular microscope used for examination of the cornea. [1] [2]
Herbert Edward Kaufman (September 28, 1931) is an American ophthalmologist who discovered idoxuridine, the first clinically useful antiviral agent; co-developed with William Bourne the clinical specular microscope to view the live corneal endothelium, co-developed timolol with Thomas Zimmerman, a new class of medications to treat glaucoma; corneal storage media for eye banks; natamycin, the ...
Scheimpflug imaging, anterior segment optical coherence tomography, confocal microscopy, and specular microscopy are additional imaging techniques that can identify the presence of guttae and quantify the thickness of the cornea. While corneal thickness can be a valuable indicator of how the cornea is changing over time, it is affected by ...
Eye examination with the aid of a slit lamp. Side view of a slit lamp machine. Cataract in human eye: magnified view seen on examination with the slit lamp. In ophthalmology and optometry, a slit lamp is an instrument consisting of a high-intensity light source that can be focused to shine a thin sheet of light into the eye.
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