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2. Drug addiction (substance use disorder) - Symptoms and causes

   www.mayoclinic.org/diseases-conditions/drug-addiction/symptoms-causes/syc-20365112

   Drug addiction, also called substance use disorder, is a disease that affects a person's brain and behavior and leads to an inability to control the use of a legal or illegal drug or medicine. Substances such as alcohol, marijuana and nicotine also are considered drugs.

3. Drug addiction (substance use disorder) - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/drug-addiction/diagnosis-treatment/drc...

   Drug addiction affects your brain and behavior to the point where you can't control your use of legal or illegal drugs, even when you know they cause harm.

4. How opioid use disorder occurs - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/in-depth/how...

   Drug addiction is defined as an out-of-control feeling that you must use a medicine or drug and continue to use it even though it causes harm over and over again. Opioids are highly addictive, largely because they trigger powerful reward centers in your brain.

5. Kratom: Unsafe and ineffective - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/in-depth/kratom/...

   And people who use kratom may begin craving it. They may need treatments given for opioid addiction, such as buprenorphine (Brixadi, Sublocade, others) and buprenorphine-naloxone (Suboxone, Zubsolv).

6. Prescription drug abuse - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/symptoms-causes/...

   Prescription drug abuse, also called prescription drug misuse, includes everything from taking a friend's prescription painkiller for your backache to snorting or injecting ground-up pills to get high. Prescription drug abuse may become ongoing and compulsive, despite the negative consequences.

7. What are opioids and why are they dangerous? - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/expert-answers/...

   Opioids are a broad group of medicines used to relieve pain. Although these medicines are effective, they can lead to addiction. Take them only as directed.

8. Teen drug abuse: Help your teen avoid drugs - Mayo Clinic

   www.mayoclinic.org/healthy-lifestyle/tween-and-teen-health/in-depth/teen-drug...

   Drug dependence. Some teens who misuse drugs are at increased risk of substance use disorder. Poor judgment. Teenage drug use is associated with poor judgment in social and personal interactions. Sexual activity. Drug use is associated with high-risk sexual activity, unsafe sex and unplanned pregnancy. Mental health disorders.

9. How to tell if a loved one is abusing opioids - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/in-depth/how-to...

   When addicted to a drug, a person will continue to use the drug even when it makes life worse. Watch for these common signs of opioid use disorder: Regularly takes an opioid in a way not meant by the healthcare professional who prescribed it.

10. Intervention: Help a loved one overcome addiction - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/mental-illness/in-depth/intervention/...

    An intervention can motivate someone to seek help for alcohol or drug misuse, compulsive eating, or other addictive behaviors. Discover when to hold one and how to make it successful. By Mayo Clinic Staff

11. Understanding drug addiction and recognizing it in yourself or...

    mcpress.mayoclinic.org/opioids/understanding-drug-addiction-and-recognizing-it...

    Drug addiction, also known as substance use disorder, is a disease that affects a person’s brain and behavior and leads to an inability to control the use of a legal or illegal drug or medication. When you’re addicted, you may continue using the drug despite the harm it causes.