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e. In probability theory, an experiment or trial (see below) is any procedure that can be infinitely repeated and has a well-defined set of possible outcomes, known as the sample space. [1] An experiment is said to be random if it has more than one possible outcome, and deterministic if it has only one. A random experiment that has exactly two ...
A randomized controlled trial (or randomized control trial; [2] RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices , diagnostic procedures , diets or other medical treatments.
e. In probability theory, the sample space (also called sample description space, [1] possibility space, [2] or outcome space[3]) of an experiment or random trial is the set of all possible outcomes or results of that experiment. [4] A sample space is usually denoted using set notation, and the possible ordered outcomes, or sample points, [5 ...
Sample size determination or estimation is the act of choosing the number of observations or replicates to include in a statistical sample. The sample size is an important feature of any empirical study in which the goal is to make inferences about a population from a sample. In practice, the sample size used in a study is usually determined ...
Intention-to-treat analysis. In medicine an intention-to-treat (ITT) analysis of the results of a randomized controlled trial is based on the initial treatment assignment and not on the treatment eventually received. ITT analysis is intended to avoid various misleading artifacts that can arise in intervention research such as non-random ...
Stratification (clinical trials) Stratification of clinical trials is the partitioning of subjects and results by a factor other than the treatment given. Stratification can be used to ensure equal allocation of subgroups of participants to each experimental condition. This may be done by gender, age, or other demographic factors.
Probability theory. In probability theory and statistics, the Bernoulli distribution, named after Swiss mathematician Jacob Bernoulli, [1] is the discrete probability distribution of a random variable which takes the value 1 with probability and the value 0 with probability . Less formally, it can be thought of as a model for the set of ...
Phases of clinical research. The phases of clinical research are the stages in which scientists conduct experiments with a health intervention to obtain sufficient evidence for a process considered effective as a medical treatment. [1] For drug development, the clinical phases start with testing for drug safety in a few human subjects, then ...