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Space-filling model of the PTEN protein (blue) complexed with tartaric acid (brown) [5] Phosphatase and tensin homolog (PTEN) is a phosphatase in humans and is encoded by the PTEN gene. [6] Mutations of this gene are a step in the development of many cancers, specifically glioblastoma, lung cancer, breast cancer, and prostate cancer.
PTEN also refers to a member of the class, phosphatase and tensin homolog. [ citation needed ] This enzyme participates in 10 metabolic pathways : inositol phosphate metabolism , phosphatidylinositol signaling system , p53 signaling pathway , focal adhesion , tight junction , endometrial cancer , glioma , prostate cancer , melanoma , and small ...
Higher RDW values indicate greater variation in size. Normal reference range of RDW-CV in human red blood cells is 11.5–15.4%. [2] [1] If anemia is observed, RDW test results are often used together with mean corpuscular volume (MCV) results to determine the possible causes of the anemia. It is mainly used to differentiate an anemia of mixed ...
In biochemistry, a phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol. Because a phosphatase enzyme catalyzes the hydrolysis of its substrate , it is a subcategory of hydrolases . [ 1 ]
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
The enzyme phosphatidylinositol-3-phosphatase (EC 3.1.3.64) catalyzes the reaction 1-phosphatidyl-1D-myo-inositol 3-phosphate + H 2 O 1-phosphatidyl-1D-myo-inositol + phosphate. This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds.
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PTEN may mean: Prime Time Entertainment Network; PTEN (gene), a human tumour suppressor gene on chromosome 10 (and its protein: phosphatase and tensin homolog)