Search results
Results from the WOW.Com Content Network
CHIR99021 is a chemical compound which acts as an inhibitor of the enzyme GSK-3. [1] It has proved useful for applications in molecular biology involving the ...
An example of a Gastruloid formed from Brachyury::GFP mouse ESCs, treated with a pulse of the Wnt/β-Catenin agonist CHIR99021 between 48 and 72h and imaged by wide-field fluorescence microscopy at 120h. Notice the polarised expression of Brachyury::GFP (Bra) at the elongating tip of the Gastruloid.
SB431542 can also be used in combination with LDN193189, CHIR99021 and DAPT to transform astrocytes into neurons. [2] It is also commonly used for immunological studies, for instance as a TGF-β inhibitor to facilitate the generation of dendritic cells from peripheral blood monocytes .
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues. First discovered in 1980 as a regulatory kinase for its namesake, glycogen synthase (GS), [2] GSK-3 has since been identified as a protein kinase for over 100 different proteins in a variety of different pathways.
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate
Rudolf Jaenisch (born on April 22, 1942) is a professor of biology at MIT and a founding member of the Whitehead Institute for Biomedical Research. [1] He is a pioneer of transgenic science, in which an animal’s genetic makeup is altered.
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate
Embryonic stem cells of the inner cell mass are pluripotent, meaning they are able to differentiate to generate primitive ectoderm, which ultimately differentiates during gastrulation into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm.