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Clostridium botulinum is a gram-positive, [1] rod-shaped, anaerobic, spore-forming, motile bacterium with the ability to produce botulinum toxin, which is a neurotoxin. [ 2 ] [ 3 ] C. botulinum is a diverse group of pathogenic bacteria .
The toxin is the protein botulinum toxin produced under anaerobic conditions (where there is no oxygen) [37] by the bacterium Clostridium botulinum. [38] Clostridium botulinum is a large anaerobic Gram-positive bacillus that forms subterminal endospores. [39] There are eight serological varieties of the bacterium denoted by the letters A to H.
Some pathogens, such as Clostridium botulinum, the source of botulism, are anaerobic. M: Moisture Water is essential for the growth of foodborne pathogens. Water activity (a w) is a measure of the water available for use and is measured on a scale of 0 to 1.0. Foodborne pathogens grow best in foods that have a w between 0.95 and 1.0.
Clostridium species are readily found inhabiting soils and intestinal tracts. Clostridium species are also a normal inhabitant of the healthy lower reproductive tract of females. [14] The main species responsible for disease in humans are: [15] Clostridium botulinum can produce botulinum toxin in food or wounds and can cause botulism.
Botulism (Type A Clostridium botulinum) in Peoria, Illinois. 28 persons were hospitalized, and 20 patients were treated with an antitoxin. 12 patients required ventilatory support and 1 death resulted. The source was sautéed onions made from fresh raw onions served on a patty melt sandwich.
A problem was first noticed by Fonterra in March 2013 when testing suggested the possible presence of Clostridium, a sometimes-dangerous class of bacteria which is often harmless. [3] On 31 July 2013, tests revealed signs of Clostridium botulinum, leading to the recall. The contamination was blamed on unsterilised pipes used to move the whey ...
However, the genus does contain some human pathogens (outlined below). The toxins produced by certain members of the genus Clostridium are among the most dangerous known. Examples are tetanus toxin (known as tetanospasmin) produced by C. tetani and botulinum toxin produced by C. botulinum.
For example, Clostridium botulinum spoils food such as meat and poultry, and Bacillus cereus, which spoils almost all type of food. When stored or subjected to unruly conditions, the organisms will begin to breed apace, releasing harmful toxins that can cause severe illness, even when cooked safely.