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Elivaldogene autotemcel, sold under the brand name Skysona, is a gene therapy used to treat cerebral adrenoleukodystrophy (CALD). It was developed by Bluebird Bio and was given breakthrough therapy designation by the US Food and Drug Administration in May 2018.
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
The Milwaukee brace, also known as a cervico-thoraco-lumbo-sacral orthosis or CTLSO, is a back brace most often used in the treatment of spinal curvatures (such as scoliosis or kyphosis) in children but also, more rarely, in adults to prevent collapse of the spine and associated pain and deformity.
The Boston brace, a type of thoraco-lumbo-sacral-orthosis (TLSO), [1] is a back brace used primarily for the treatment of idiopathic scoliosis in children. [2] It was developed in 1972 by M.E "Bill" Miller and John Hall at the Boston Children's Hospital in Boston , Massachusetts .
Sodium thiopental is an ultra-short-acting barbiturate and has been used commonly in the induction phase of general anesthesia.Its use has been largely replaced with that of propofol, but may retain some popularity as an induction agent for rapid-sequence induction and intubation, such as in obstetrics. [12]
Alipogene tiparvovec was expected to cost around US$1.6 million per treatment in 2012, [9] —revised to $1 million in 2015, [10] —making it the most expensive medicine in the world at the time. [11] However, replacement therapy, a similar treatment, can cost over $300,000 per year, for life. [4]
Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024 [update] , the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation . [ 2 ] [ 3 ] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from ...
Intraosseous access has roughly the same absorption rate as IV access, and allows for fluid resuscitation. For example, sodium bicarbonate can be administered IO during a cardiac arrest when IV access is unavailable. [1] High flow rates are attainable with an IO infusion, up to 125 milliliters per minute.