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Furosemide, sold under the brand name Lasix among others, is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease. [4] Furosemide may also be used for the treatment of high blood pressure . [ 4 ]
Loop diuretics usually have a ceiling effect whereby doses greater than a certain maximum amount will not increase the clinical effect of the drug. Also, there is a threshold minimum concentration of loop diuretics that needs to be achieved at the thick ascending limb to enable the onset of abrupt diuresis.
In medicine, diuretics are used to treat heart failure, liver cirrhosis, hypertension, influenza, water poisoning, and certain kidney diseases.Some diuretics, such as acetazolamide, help to make the urine more alkaline, and are helpful in increasing excretion of substances such as aspirin in cases of overdose or poisoning.
Depression among people with diabetes remains a key health area to address. There has been recent interest in whether glucagon-like peptide-1 receptor agonists (GLP-1RAs) affect depression risk.
Very common (>10% incidence) adverse effects include: Somnolence † (produces an intermediate degree of sedation compared to other atypical antipsychotics [4]) Akathisia † Fasting glucose increased † Nausea † Parkinsonism † Insomnia † † These are dose-dependent.
As with any prescription medication, there are side effects of Wegovy to keep in mind. The most common side effects are gastrointestinal ones, like: Nausea. Vomiting. Heartburn. Diarrhea. Constipation
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These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.