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In Italy, the pill must be prescribed and used in a clinical structure and is not sold at chemists. [132] It was approved in Hungary in 2005, but as of 2005 had not been released on the market yet, and was the target of protests. [133] Mifepristone is licensed in Ireland for use of abortions up to 12 weeks since it was legalised in 2018. [134]
Estradiol valerate/cyproterone acetate (Femilar) was introduced for use as a birth control pill in Finland in 1993, but was never marketed elsewhere. [235] Subsequently, estradiol valerate/dienogest (Natazia, Qlaira) was marketed as a birth control pill in 2008 [236] and estradiol/nomegestrol acetate (Naemis, Zoely) was introduced in 2012. [128]
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
Phenylpropanolamine (PPA), sold under many brand names, is a sympathomimetic agent which is used as a decongestant and appetite suppressant. [9] [1] [10] [11] It was previously commonly used in prescription and over-the-counter cough and cold preparations.
The Schedule J of the Drugs and Cosmetics Rules, 1945 of India contains "a list of diseases and ailments which a drug may not claim to prevent or cure".Under Rule 106 of the Drugs and Cosmetics Act, 1940, a drug cannot make claims to treat or prevent any of the diseases or reform the conditions listed.
Lonidamine is a derivative of indazole-3-carboxylic acid, which for a long time, has been known to inhibit aerobic glycolysis in cancer cells. It seems to enhance aerobic glycolysis in normal cells, but suppress glycolysis in cancer cells.
Primidone, sold under various brand names (including Mysoline), is a barbiturate medication that is used to treat partial and generalized seizures [7] and essential tremors. [8]