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Obesity hypoventilation syndrome is defined as the combination of obesity and an increased blood carbon dioxide level during the day that is not attributable to another cause of excessively slow or shallow breathing. [2] The most effective treatment is weight loss, but this may require bariatric surgery to achieve. [3]
Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (hypo meaning "below") to perform needed respiratory gas exchange. [1] By definition it causes an increased concentration of carbon dioxide ( hypercapnia ) and respiratory acidosis .
The treatment for concentral hypoventilation syndrome involves breathing support during sleep, often through the assistance of a mechanical ventilator. In some cases, this type of breathing support may be necessary during waking hours as well. Often referred to as oxygen therapy, it can use a CPAP machine as well.
Obesity, in general, can increase your risk of: High blood pressure. High cholesterol. Type 2 diabetes. Breathing problems. Joint problems and back pain . Stroke. Depression. Anxiety. Fatty liver ...
The most effective treatment for obesity is bariatric surgery. [7] Surgery for severe obesity is associated with long-term weight loss and decreased overall mortality. One study found a weight loss of between 14% and 25% (depending on the type of procedure performed) at 10 years, and a 29% reduction in all cause mortality when compared to ...
The fact that obesity affects more than a third of American adults today has attracted many biotech investors to these stocks, but many may not fully understand how physicians approach treatment ...
Hypercapnia is generally caused by hypoventilation, lung disease, or diminished consciousness. It may also be caused by exposure to environments containing abnormally high concentrations of carbon dioxide, such as from volcanic or geothermal activity, or by rebreathing exhaled carbon dioxide .
“This study highlights BCL6 as a potential therapeutic target for muscle loss due to aging, cancer cachexia, obesity and complications from its treatment (e.g., GLP-1 receptor agonists), which ...
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