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Initial dose: 150 mg orally per day in 2 or 3 divided doses. Both the efficacy and adverse event profile of this drug have been shown to be dose dependent; the effect of dose escalation rate on tolerability of this drug has not been formally studied.
The maximum recommended dose of LYRICA is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 mL/min. Begin dosing at 50 mg three times a day (150 mg/day). The dose may be increased to 300 mg/day within 1 week based on efficacy and tolerability.
The usual dose is 3.5 milligram per kilogram (mg/kg) per day given in 3 divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 14 mg/kg per day.
Initial: 75 mg PO q12hr (150 mg/day) Maintenance: May increase to 150mg q12hr after 1 week as needed; recommended dose is 300-400 mg/day. Owing to dose-dependent adverse reactions, doses...
The maximum recommended dose of LYRICA is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 mL/min. Begin dosing at 50 mg three times a...
Immediate release: Oral: Initial: 75 mg twice daily; may increase to 150 mg twice daily within 1 week based on response and tolerability; maximum dose: 450 mg/day (manufacturer's labeling). Note: Some experts suggest lower initial doses of 25 to 50 mg at bedtime; some patients may respond to maintenance doses <300 mg/day (Goldenberg 2018).
In general, it is recommended that patients be started on a total daily dose no greater than 150 mg/day (75 mg two times a day, or 50 mg three times a day). Based on individual patient...