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SIRVA is caused by improper insertion of the needle used in injections. It is "a preventable occurrence caused by the injection of a vaccine into the shoulder capsule rather than the deltoid muscle. As a result, inflammation of the shoulder structures causes patients to experience pain, a decreased range of motion, and a decreased quality of life."
Some reactions, such as pain, may appear immediately. Others may be delayed, such as erythema which may appear 24–96 hours after injection. [2] ISRs commonly seen with subcutaneous injections include: Bleeding and bruising [3] Erythema (redness) Pain; Pruritis (itching) [4] Swelling [5] Induration (hardening of the skin) [6] Discoloration [6]
A Novo Nordisk study included 2,000 participants with obesity or overweight and a weight-related health condition (excluding type 2 diabetes) who were given a 2.4 mg dose of semaglutide for 68 ...
Overall, side effects from a half-strength third dose of Moderna's vaccine were similar to a second dose. Younger people recorded more side effects.
Redness and pain at the site of injection occur in between 25% and 85% of people. [2] Fever, feeling tired, and minor muscle pain occurs in less than 10% of people. [2] Severe allergic reactions occur in fewer than one in 100,000 people. [2]
The company previously announced that clinical trial participants lost an average of 17.4 percent of their baseline body weight after 68 weeks of using this new oral formulation. Those who took a ...
Fear of needles, also called needle phobia, is also common and may result in anxiety and fainting before, during, or after an injection. To prevent the localized pain that occurs with injections the injection site may be numbed or cooled before injection and the person receiving the injection may be distracted by a conversation or similar means.
Depending on the formulation it can be given by injection into muscle, a vein, or under the skin. [13] The effects last a few weeks. [14] Common side effects include pain at the site of injection, muscle pain, and allergic reactions. [13] Other severe side effects include kidney problems, anaphylaxis, blood clots, and red blood cell breakdown. [13]