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Mantle cell lymphoma is a blood cancer that starts in white blood cells in your lymph nodes. There’s no cure for mantle cell lymphoma, but there are treatments that put the condition into remission.
Each year 4,000 people in the U.S. are diagnosed with mantle cell lymphoma. And while this disease is rare, experts have come up with new ways to treat the disease in recent years. Learn about mantle cell lymphoma symptoms, diagnosis and treatment options from Michael Wang, M.D.
Treatment. Most people with mantle cell lymphoma will begin treatment right after diagnosis and staging of the cancer.
Treatments for mantle cell lymphoma are rapidly evolving and include chemotherapy-free treatment options and new forms of targeted therapy and immunotherapy, including new types of CAR T-cell therapy and bispecific antibodies.
As 1L treatments become more effective, improving tolerability is also becoming an increasingly realistic goal. Targeted agents, which are now mainstays of treatment in R/R MCL, are establishing new, paradigm-changing roles in frontline treatment.
In addition, in relapsed/refractory mantle cell lymphoma, there are a number of promising therapies beyond covalent BTK inhibitors, including novel immunotherapeutics such as CAR T-cell therapy and bispecific antibodies.
Initial treatment approaches for aggressive MCL in younger patients include combination chemotherapy, typically in combination with the monoclonal antibody rituximab (Rituxan), as first-line treatment, followed by autologous stem cell transplantation (in which patients receive their own stem cells), though rituximab is not specifically approved ...
Mantle cell lymphoma attacks the white blood cells that help your body fight infections. Here’s what you need to know about how this cancer spreads and your treatment options.
Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma with historically poor long-term survival compared with other B-cell malignancies. Treatment strategies for this disease are variable and dependent on symptoms and patient fitness.
To treat lymphoma properly, your care team has to establish the exact subtype of the cancer. This requires collecting a sample of the potentially cancerous tissue, with a procedure called a biopsy, and sending it to a laboratory for testing and analysis.