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Pulmonary embolism is blood clots occurring in the lungs. Restricted blood flow in the pulmonary circulation results in alveoli ventilated but not perfused, thus, increasing the V/Q ratio and decreasing gas exchange. It can cause hypoxemia(low oxygen level) and damage part of the lung, which may be treated with anticoagulants.
Oxygenated blood leaves the lungs through pulmonary veins, which return it to the left part of the heart, completing the pulmonary cycle. [3] [6] This blood then enters the left atrium, which pumps it through the mitral valve into the left ventricle. [3] [6] From the left ventricle, the blood passes through the aortic valve to the aorta.
All the blood returning from the body tissues to the right side of the heart flows through the alveolar capillaries before being pumped around the body again. On its passage through the lungs the blood comes into close contact with the alveolar air, separated from it by a very thin diffusion membrane which is only, on average, about 2 μm thick ...
Breathing, or external respiration, brings air into the lungs where gas exchange takes place in the alveoli through diffusion. The body's circulatory system transports these gases to and from the cells, where cellular respiration takes place. [2] [3] The breathing of all vertebrates with lungs consists of repetitive cycles of inhalation and ...
The efficiency of gas exchange is significantly influenced by the distribution and adequacy of blood flow, or perfusion, to various parts of the lungs. In a healthy lung, perfusion is optimally matched with ventilation (airflow), ensuring efficient gas exchange. [8] In vivo lung perfusion occurs within the living organism and is tightly ...
In the lungs, oxygen from the inhaled air is transferred into the blood and circulated throughout the body. Carbon dioxide (CO 2) is transferred from returning blood back into gaseous form in the lungs and exhaled through the lower respiratory tract and then the upper, to complete the process of breathing.
Exchange of gases in the lung occurs by ventilation and perfusion. [1] Ventilation refers to the in-and-out movement of air of the lungs and perfusion is the circulation of blood in the pulmonary capillaries. [1] In mammals, physiological respiration involves respiratory cycles of inhaled and exhaled breaths.
This matching may be assessed in the lung as a whole, or in individual or in sub-groups of gas-exchanging units in the lung. On the other side Ventilation-perfusion mismatch is the term used when the ventilation and the perfusion of a gas exchanging unit are not matched. The actual values in the lung vary depending on the position within the lung.