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Most commonly emphysema refers to the permanent enlargement of air spaces in the lungs, [5] [6] and is also known as pulmonary emphysema. Emphysema is a lower respiratory tract disease, [ 7 ] characterised by enlarged air-filled spaces in the lungs , that can vary in size and may be very large.
Diffuse alveolar damage (DAD) is a histologic term used to describe specific changes that occur to the structure of the lungs during injury or disease.Most often DAD is described in association with the early stages of acute respiratory distress syndrome (). [1]
A lung cyst, or pulmonary cyst, encloses a small volume of air, and has a wall thickness of up to 4 mm. [3] A minimum wall thickness of 1 mm has been suggested, [3] but thin-walled pockets may be included in the definition as well. [4] Pulmonary cysts are not associated with either smoking or emphysema. [5]
Restrictive lung disease is characterized by reduced lung volumes, and therefore reduced lung compliance, either due to an intrinsic reason, for example a change in the lung parenchyma, or due to an extrinsic reason, for example diseases of the chest wall, pleura, or respiratory muscles. [3]
There are three main causes of PPHN are parenchymal diseases such as meconium aspiration syndrome, idiopathic, and hypoplastic vasculature like in a diaphragmatic hernia. It will eventually resolve in most infants. [22] This is the only syndrome that inhaled nitric oxide is approved for by the FDA. [23] Pulmonary interstitial emphysema
Well-demarcated, nodular lesions ranging 2–5 mm in pulmonary parenchyma. Type II pneumocytes without nuclear atypia lined thickened alveolar septa and proliferated papillary structures. Enlarged cuboidal cells lining mildly thickened alveolar septa. [11] Enlarged cuboidal cells have abundant, eosinophilic cytoplasm and large, round nuclei. [12]
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