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Structurally it actually methyl-metronidazole. Effectiveness in the treatment of dientamoebiasis has been reported. [1] It has also been tested against Atopobium vaginae. [2] In the United States, secnidazole is FDA approved for the treatment of bacterial vaginosis and trichomoniasis in adult women. [3]
Atopobium species are anaerobic, Gram-positive rod-shaped or elliptical bacteria found as single elements or in pairs or short chains. Atopobium vaginae was discovered in 1999. [ 2 ] This is a facultative anaerobic bacteria, which form small colonies on blood agar at 37 °C is also positive for acid phosphatase.
Fannyhessea vaginae is a species of bacteria in the family Atopobiaceae. It is a facultative anaerobic, Gram-positive rod-shaped or elliptical coccobacillus found as single elements or in pairs or short chains. [2] It is typically isolated from 80% of women with bacterial vaginosis and it is implicated in treatment failures.
O'Hanlon [12] and Baeten [24] found that 96% of Lactobacillus species from a healthy vaginal ecosystem produced H 2 O 2 (L. jensenii and L. vaginalis produce the highest levels of H 2 O 2), [11] [25] whereas only 6% of the lactobacilli recovered from women with BV produced H 2 O 2. [19]
Atopobium, Olsenella, and Cryptobacterium species have responsible for human oral infections including periodontitis, halitosis, and other endodontic infections. [ 9 ] [ 10 ] Eggerthella species have been associated with severe blood bacteraemia and ulcerative colitis .
[1] [2] The normally predominant species of Lactobacilli are markedly reduced. [3] This is the list of organisms that are found in the vagina that are associated with bacterial vaginosis, an infectious disease of the vagina caused by excessive growth of specific bacteria.
[2] While the vaginal microbiota is populated predominantly by Lactobacillus spp. in 71% of women, 29% of asymptomatic, healthy women possess a microbiota essentially lacking in Lactobacillus and instead the following groups have been isolated from this population.
Over-the-counter (OTC) medicines at FamilyDoctor.org, maintained by the American Academy of Family Physicians. Contains extensive information on over-the-counter drugs and their responsible use, including specific guidance on several drug classes in question-and-answer format and information on common drug interactions.