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The opposite of LTP is long-term depression, which produces a long-lasting decrease in synaptic strength. It is one of several phenomena underlying synaptic plasticity , the ability of chemical synapses to change their strength.
In neurophysiology, long-term depression (LTD) is an activity-dependent reduction in the efficacy of neuronal synapses lasting hours or longer following a long patterned stimulus. LTD occurs in many areas of the CNS with varying mechanisms depending upon brain region and developmental progress.
Impermanence, also known as the philosophical problem of change, is a philosophical concept addressed in a variety of religions and philosophies. In Eastern philosophy it is notable for its role in the Buddhist three marks of existence .
Much of the work on long-lasting synaptic changes between vertebrate neurons (such as long-term potentiation) involves the use of non-physiological experimental stimulation of brain cells. However, some of the physiologically relevant synapse modification mechanisms that have been studied in vertebrate brains do seem to be examples of Hebbian ...
In these cases of planned obsolescence, there is an information asymmetry between the producer, who knows how long the product was designed to last, and the customer, who does not. When a market becomes more competitive, product lifespans tend to increase.
7 patterns of long-lasting relationships, according to a couples therapist. Ani Freedman. Updated September 24, 2024 at 10:28 AM. Getty Images. ... Don’t try to change your partner.
A species had an irreducible functional complexity, and "none of its parts can change without the others changing too". [11] Evolutionists expected one part to change at a time, one change to follow another. In Cuvier's view, evolution was impossible, as any one change would unbalance the whole delicate system. [11]
Democratic backsliding [a] is a process of regime change toward autocracy in which the exercise of political power becomes more arbitrary and repressive. [7] [8] [9] The process typically restricts the space for public contest and political participation in the process of government selection.