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Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [ 4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [ 3][ 5] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [ 2] Reintroduced 2002 with restricted indication and ...
Of course, for some people, relief can come in the form of over-the-counter medications like acetaminophen (Tylenol), ibuprofen (Advil, Motrin IB), and naproxen (Aleve), which can help lessen pain ...
[citation needed] It is also used to treat joint pain like arthritis, [2] [3] general back pain, [4] and headaches. [citation needed] It is found in a variety of over-the-counter (OTC) medications, most notably the brand Doan's Pills, as an anti-inflammatory, primarily for back-pain relief. Magnesium salicylate can be an effective OTC ...
The pain medication paracetamol (acetaminophen) is the first line treatment for osteoarthritis. [60] [94] Pain relief does not differ according to dosage. [61] However, a 2015 review found acetaminophen to have only a small short-term benefit with some laboratory concerns of liver inflammation. [95]
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