Ads
related to: estrogen receptor alpha polymorphism test for prostate cancer blood work- Understand Your Diagnosis
Bring Clarity to the Uncertainty by
Downloading Our Free Test Guide.
- Why Test With Prolaris?
Get Information About Your Cancer's
Behavior & How to Best Treat It.
- Understand Your Diagnosis
Search results
Results from the WOW.Com Content Network
The estrogen receptor test (ERT) is a laboratory test to determine whether cancer cells have estrogen receptors.This information can guide treatment of the cancer. [1]The test uses immunohistochemical techniques on the estrogen receptor (ER).
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor (mainly found as a chromatin-binding protein [5]) that is activated by the sex hormone estrogen. In humans, ERα is encoded by the gene ESR1 (EStrogen Receptor 1). [6] [7] [8]
2101 26379 Ensembl ENSG00000173153 ENSMUSG00000024955 UniProt P11474 O08580 RefSeq (mRNA) NM_001282450 NM_001282451 NM_004451 NM_007953 RefSeq (protein) NP_001269379 NP_001269380 NP_004442 NP_031979 Location (UCSC) Chr 11: 64.31 – 64.32 Mb Chr 19: 6.89 – 6.9 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Estrogen-related receptor alpha (ERRα), also known as NR3B1 (nuclear ...
Estrogen receptors were first identified by Elwood V. Jensen at the University of Chicago in 1958, [45] [46] for which Jensen was awarded the Lasker Award. [47] The gene for a second estrogen receptor (ERβ) was identified in 1996 by Kuiper et al. in rat prostate and ovary using degenerate ERalpha primers. [48]
Reflect the stage of cancer; By determining the stage of cancer, it's possible to give a prognosis and treatment plan. [3] Screening for cancers; No screening test is wholly specific, and a high level of tumor marker can still be found in benign tumors. The only tumor marker currently used in screening is PSA (prostate-specific antigen ...
The ERRs are orphan nuclear receptors, meaning the identity of their endogenous ligand has yet to be unambiguously determined. They are named because of sequence homology with estrogen receptors, but do not appear to bind estrogens or other tested steroid hormones. There are three human estrogen related receptors: ERRα ; ERRβ ; ERRγ
In animal studies, GTx-758 reversibly suppresses testosterone concentrations to castrate levels, reduces prostate size and levels of prostate-specific antigen (PSA), but does not induce typical side effects associated with hyperestrogenism (or hypoestrogenism) including hot flashes, bone loss, thrombophilia, hypercoagulation, or increased body fat. [1]
HDE and pseudopregnancy have been used in medicine for a number of hormone-dependent indications, such as breast cancer, prostate cancer, and endometriosis, among others. [ 1 ] [ 7 ] [ 2 ] Both natural or bioidentical estrogens and synthetic estrogens have been used and both oral and parenteral routes may be used.
Ads
related to: estrogen receptor alpha polymorphism test for prostate cancer blood work