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Conivaptan, sold under the brand name Vaprisol, is a non-peptide inhibitor of the receptor for anti-diuretic hormone, also called vasopressin. It was approved in 2004 for hyponatremia (low blood sodium levels).
The "vaptan" drugs act by directly blocking the action of vasopressin at its receptors (V 1A, V 1B and V 2).These receptors have a variety of functions, with the V 1A and V 2 receptors are expressed peripherally and involved in the modulation of blood pressure and kidney function respectively, while the V 1A and V 1B receptors are expressed in the central nervous system.
In 2001, the union's independently conducted poll of 6,000 registered nurses in the state found that 56 percent of nurses would enter the profession today due to mandatory overtime and poor nurse-to-patient staffing ratios. At the time, the poll was the largest survey of RNs ever conducted in Pennsylvania. [20]
A systematic review of 63 trials with over 35,000 participants indicated β-blockers increased the risk of mortality, compared to other antihypertensive therapies. [15] They do, however, have an important role in the prevention of heart attacks in people who have already had a heart attack. [37]
A Pennsylvania nurse who administered lethal or potentially lethal doses of insulin to numerous patients pleaded guilty to three counts of murder and other charges Thursday and was sentenced to ...
Tolvaptan, sold under the brand name Samsca among others, is an aquaretic drug that functions as a selective, competitive vasopressin receptor 2 (V 2) antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
On February 23, 2011, Becker's Hospital Review included Lehigh Valley Hospital–Cedar Crest among its listing of the "50 Best Hospitals in America" report. [7] It is also a three time certified National Magnet Hospital for nursing excellence from the American Nurses Credentialing Center.
St. Mary Medical Center, is a non-profit hospital located in Langhorne, Pennsylvania. The hospital has a Level II Trauma Center and employs over 700 physicians and 1,100 volunteers. The hospital focuses on non-invasive treatments, adult and pediatric emergency services, rehabilitation and health and wellness programs.