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For example, the British National Formulary uses the cautions versus contraindications pair, and various U.S. CDC webpages use precautions versus contraindications. The logic of the latter two styles is the idea that readers must never be confused: the word contraindication in that usage always is meant in its absolute sense , providing ...
Common Examples Mechanism of benefit and effect Side effects, caution & contraindications Remarks Beta-blockers: Metoprolol; Atenolol; Bisoprolol; Block beta-1 receptors in the heart → stop the effects of catecholamines on the heart→ reduce heart rate, heart contractility and conduction velocity → reduce the workload of the heart [15 ...
Examples of CYP3A4 inhibitors include clarithromycin, verapamil, ketoconazole and anti-viral drugs, including nirmatrelvir and ritonavir. [7] These medications should not be administered with triamcinolone as drug-drug interactions may result.
Examples are brotizolam, midazolam, and triazolam. Intermediate-acting compounds have a median half-life of 12–40 hours. They may have some residual effects in the first half of the day if used as a hypnotic. Rebound insomnia, however, is more common upon discontinuation of intermediate-acting benzodiazepines than longer-acting benzodiazepines.
NSAIDs, like all medications, may interact with other medications. For example, concurrent use of NSAIDs and quinolone antibiotics may increase the risk of quinolones' adverse central nervous system effects, including seizure. [47] [48] There is an argument over the benefits and risks of NSAIDs for treating chronic musculoskeletal pain.
Contraindications [ edit ] The use of LMWHs should be avoided in patients with known allergies to LMWHs, heparin, sulfites or benzyl alcohol , in patients with active major bleeding, or in patients with a history of heparin-induced low blood platelet count (also known as heparin-induced thrombocytopenia or HIT).
Two examples include metformin and Rybelsus® (semaglutide). ... Research the safety profile of the medication, including potentially serious side effects, contraindications and warnings.
Contraindication : Allergies or hypersensitivity to alpha-1 blockers or any of the active ingredient, that includes angiodema induced by the drug. Patients with a history of orthostatic hypotension or severe hepatic impairment.