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Adrenarche is an early stage in sexual maturation that happens in some higher primates (including humans), typically peaks at around 20 years of age, [1] [2] and is involved in the development of pubic hair, body odor, skin oiliness, axillary hair, sexual attraction/sexual desire/increased libido and mild acne.
It is usually the second sign of puberty, after thelarche in females and gonadarche in males (though in females, it can also happen before thelarche, but this is less common). The early stage of sexual maturation, also known as adrenarche , is marked by characteristics including the development of pubic hair, axillary hair , adult apocrine body ...
Puberty is preceded by adrenarche, marking an increase of adrenal androgen production between ages 6–10. Adrenarche is sometimes accompanied by the early appearance of axillary and pubic hair. The first androgenic hair resulting from adrenarche can be also transient and disappear before the onset of true puberty.
In females, gonadarche is responsible for thelarche and menarche (first menstruation). [4] Gonadarche should be contrasted with adrenarche. Gonadarche indicates that true central puberty has begun, while adrenarche is an independent maturational process only loosely associated with complete puberty. [5]
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Premature thelarche is a benign condition in which a young female has breast development before age eight without any accompanied pubertal changes. [ 2 ] [ 7 ] [ 15 ] [ 16 ] Individuals undergoing isolated premature thelarche do not experience menstruation , pubic hair growth ( pubarche ), or the bone growth characteristic of puberty. [ 15 ]
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Adrenarche is independent of ACTH or gonadotropins and correlates with a progressive thickening of the zona reticularis layer of the cortex. Functionally, adrenarche provides a source of androgens for the development of axillary and pubic hair before the beginning of puberty.