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There are four paired deep cerebellar nuclei embedded in the white matter centre of the cerebellum. The nuclei are the fastigial , globose , emboliform , and dentate nuclei. In lower mammals the emboliform nucleus appears to be continuous with the globose nucleus, and these are known together as the interposed nucleus .
The human cerebellum is located at the base of the brain, with the large mass of the cerebrum above it, and the portion of the brainstem called the pons in front of it. It is separated from the overlying cerebrum by a layer of tough dura mater called the cerebellar tentorium; all of its connections with other parts of the brain travel through the pons.
The emboliform nucleus is a deep cerebellar nucleus that lies immediately to the medial side of the dentate nucleus, partly covering its hilum. It is one of the four pairs of deep cerebellar nuclei, which are from lateral to medial: the dentate, emboliform, globose and fastigial. These nuclei can be seen using Weigert's elastic stain.
The cerebellar nuclei receive afferent projections from the inferior olive, lateral reticular nucleus, upper cervical and lumbar spinal segments, and the Pontine nuclei. Together, the deep cerebellar nuclei form a functional unit that provides feedback control of the cerebellar cortex by cerebellar output. [4]
The interposed nucleus is the combined paired globose and emboliform nuclei, (deep cerebellar nuclei) on either side of the cerebellum. [1] [2] It is located in the roof of the fourth ventricle, lateral to the fastigial nucleus. The emboliform nucleus is the anterior interposed nucleus, and the globose nucleus is the posterior interposed ...
The flocculus of the flocculonodular lobe is the only part of the cerebellar cortex that does not project to the deep nuclei—its output goes to the vestibular nuclei instead. [ 11 ] The majority of neurons in the deep nuclei have large cell bodies and spherical dendritic trees with a radius of about 400 μm, and use glutamate as their ...
It brings sensory and motor information to and from the cerebellum. The arbor vitae is located deep in the cerebellum. Situated within the arbor vitae are the deep cerebellar nuclei; the dentate, globose, emboliform and the fastigial nuclei. These four different structures lead to the efferent projections of the cerebellum. [2]
The fastigial nuclei is situated atop the roof of the fourth ventricle (thence its name: "fastigus" is Latin for "summit"). [1]The fastigial nucleus is a mass of gray matter nearest to the middle line at the anterior end of the superior vermis, immediately over the roof of the fourth ventricle (the peak of which is called the fastigium), from which it is separated by a thin layer of white matter.