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There are four paired deep cerebellar nuclei embedded in the white matter centre of the cerebellum. The nuclei are the fastigial , globose , emboliform , and dentate nuclei. In lower mammals the emboliform nucleus appears to be continuous with the globose nucleus, and these are known together as the interposed nucleus .
The human cerebellum is located at the base of the brain, with the large mass of the cerebrum above it, and the portion of the brainstem called the pons in front of it. It is separated from the overlying cerebrum by a layer of tough dura mater called the cerebellar tentorium; all of its connections with other parts of the brain travel through the pons.
The whole cerebellum has only one output, which necessarily leads from the deep cerebellar nuclei. There is output from the cerebellar cortex, so this output must go through the cerebellar nuclei and send output to rest of nervous system. Thus, the cerebellum communicates to the outside world via the cerebellar nuclei. Input that reaches the ...
It brings sensory and motor information to and from the cerebellum. The arbor vitae is located deep in the cerebellum. Situated within the arbor vitae are the deep cerebellar nuclei; the dentate, globose, emboliform and the fastigial nuclei. These four different structures lead to the efferent projections of the cerebellum. [2]
The emboliform nucleus is a deep cerebellar nucleus that lies immediately to the medial side of the dentate nucleus, partly covering its hilum. It is one of the four pairs of deep cerebellar nuclei, which are from lateral to medial: the dentate, emboliform, globose and fastigial. These nuclei can be seen using Weigert's elastic stain.
It sends fibers to deep cerebellar nuclei that, in turn, project to both the cerebral cortex and the brain stem, thus providing modulation of descending motor systems. [ 14 ] The lateral zone, which in humans is by far the largest part, constitutes the cerebrocerebellum, also known as neocerebellum.
The IO sends signals to the cerebellum based on information sent from the spino-olivary tract. Regulation following this point is highly debated. The original hypothesis as to how the IO influenced the cerebellum involved long term depression (LTD). [2] In this scenario, deep cerebellar nuclei send GABA projection to
Embryonic vertebrate subdivisions of the developing human brain hindbrain or rhombencephalon is a developmental categorization of portions of the central nervous system in vertebrates. It includes the medulla , pons , and cerebellum .