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Intravenous Ascorbic Acid or PAA, pharmacologic ascorbic acid [1] (also known as vitamin C or L-ascorbic acid), is a process that delivers soluble ascorbic acid directly into the bloodstream. It is not approved for use to treat any medical condition.
People in sepsis may have micronutrient deficiencies, including low levels of vitamin C. [60] An intravenous intake of doses much higher than the RDA, such as 3 g/d or more, appears to be needed to maintain normal plasma concentrations in people with sepsis, as the body's demand for Vitamin C may increase significantly due to the heightened ...
People in sepsis may have micronutrient deficiencies, including low levels of vitamin C. [113] An intravenous intake of doses much higher than the RDA, such as 3 g/d or more, appears to be needed to maintain normal plasma concentrations in people with sepsis, as the body's demand for vitamin C may increase significantly due to the heightened ...
People in sepsis may have micronutrient deficiencies, including low levels of vitamin C. [102] Reviews mention that an intake of 3.0 g/day, which requires intravenous administration, may be needed to maintain normal plasma concentrations in people with sepsis or severe burn injury. [103] [104]
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.
Tentative experiments in the 1930s by Claus W. Jungeblut [16] with larger doses of vitamin C led to Frederick Klenner's development of megadose intravenous vitamin C treatments for polio and other viruses in the 1940s. [17]
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To ensure that the drug taker who has poor absorption is dosed appropriately, the bottom value of the deviation range is employed to represent real bioavailability and to calculate the drug dose needed for the drug taker to achieve systemic concentrations similar to the intravenous formulation. [4] To dose without knowing the drug taker's ...