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Occasionally, during pregnancy, there is a single umbilical artery (SUA) present in the umbilical cord, as opposed to the usual two. [1] This is sometimes also called a two-vessel umbilical cord, or two-vessel cord. Approximately, this affects between 1 in 100 and 1 in 500 pregnancies, making it the most common umbilical abnormality.
Features secondary to VACTERL components are frequent enough to be considered an extension of VACTERL. These include: single umbilical artery, ambiguous genitalia, abdominal wall defects, diaphragmatic hernia, intestinal and respiratory anomalies, and oligohydramnios sequence defects. [4] [8] Cardiac defects are thought to fit in this category. [4]
The umbilical cord lining is a good source of mesenchymal and epithelial stem cells. Umbilical cord mesenchymal stem cells (UC-MSC) have been used clinically to treat osteoarthritis, autoimmune diseases, and multiple other conditions. Their advantages include a better harvesting, and multiplication, and immunosuppressive properties that define ...
The umbilical arteries are actually the anterior division of the internal iliac arteries, and retain part of this function after birth. [3] The umbilical arteries are one of two arteries in the human body, that carry deoxygenated blood, the other being the pulmonary arteries. The pressure inside the umbilical artery is approximately 50 mmHg. [4]
The most prevalent defect in about 1% of fetuses' umbilical region is a single umbilical artery. [30] When a single umbilical artery is found, more tests are run including a detailed ultrasound to detect any other developmental abnormalities that may be the result of the single artery, genetic deviation, or other causes.
Twin-to-twin transfusion syndrome (TTTS), also known as feto-fetal transfusion syndrome (FFTS), twin oligohydramnios-polyhydramnios sequence (TOPS) and stuck twin syndrome, is a complication of monochorionic multiple pregnancies (the most common form of identical twin pregnancy) in which there is disproportionate blood supply between the fetuses.
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Newborn infant with Rhesus disease, a type of hemolytic disease of the newborn, suffering from hydrops fetalis.The infant did not survive. [4]Hydrops fetalis usually stems from fetal anemia, when the heart needs to pump a much greater volume of blood to deliver the same amount of oxygen.