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Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. [5] For heart failure, it is generally used with a diuretic , such as furosemide . [ 6 ]
ATC code C04 Peripheral vasodilators is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. [1] [2] This class of medicine works by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.
Enalaprilat is the active metabolite of enalapril. It is the first dicarboxylate-containing ACE inhibitor and was developed partly to overcome these limitations of captopril . The thiol functional group of captopril was replaced with a carboxylic acid group, but additional modifications were required to achieve a potency similar to captopril.
Enalapril/hydrochlorothiazide, sold under the brand name Vaseretic among others, is a fixed-dose combination medication used for the treatment of hypertension (high blood pressure). [2] It contains enalapril , an angiotensin converting enzyme inhibitor , and hydrochlorothiazide a diuretic . [ 2 ]
Arteriolar vasodilators are substances or medications that preferentially dilate arterioles.When used on people with certain heart conditions, it causes a phenomenon known as the cardiac steal syndrome.
A cerebral vasodilator is a drug which acts as a vasodilator in the brain. [1] [2] They are used to improve blood flow in people with cerebrovascular insufficiency and to treat neurological disorders secondary to this condition. [2] A number of different cerebral vasodilators exist.
A nitrovasodilator is a pharmaceutical agent that causes vasodilation (widening of blood vessels) by donation of nitric oxide (NO), [1] and is mostly used for the treatment and prevention of angina pectoris. This group of drugs includes nitrates (esters of nitric acid), which are reduced to NO in the body, as well as some other substances.