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Osteoporosis, including drug- and cancer-related osteoporosis, giant cell tumour of bone and hypercalcaemia of malignancies: Hypercholesterolaemia, cataract, urinary retention, hypocalcaemia, osteonecrosis of the jaw and anaphylaxis. Gemtuzumab ozogamicin: IV: CD33 antibody that induces apoptosis of the tagged cell. Acute myeloid leukaemia
Vasculitis is a group of disorders that destroy blood vessels by inflammation. [2] Both arteries and veins are affected. Lymphangitis (inflammation of lymphatic vessels) is sometimes considered a type of vasculitis. [3] Vasculitis is primarily caused by leukocyte migration and resultant damage.
Classification Group Diseases Large-vessel vasculitis (LVV) Takayasu's arteritis (TAK); Giant-cell arteritis (GCA) Medium-vessel vasculitis (MVV) Polyarteritis nodosa (PAN), Kawasaki disease (KD) Small vessel vasculitis (SVV) ANCA-associated vasculitis (AAV); Immune complex SVV Variable vessel vasculitis (VVV) Behcet's disease (BD); Cogan's ...
Necrotizing vasculitis, also called systemic necrotizing vasculitis, [1] is a general term for the inflammation of veins and arteries that develops into necrosis and narrows the vessels. [ 2 ] Tumors , medications, allergic reactions , and infectious organisms are some of the recognized triggers for these conditions, even though the precise ...
Avacopan, sold under the brand name Tavneos, is a medication used to treat anti-neutrophil cytoplasmic autoantibody-associated vasculitis. [ 5 ] [ 6 ] [ 8 ] Avacopan is a complement 5a receptor antagonist [ 5 ] and a cytochrome P450 3A4 inhibitor.
a vasculitis of small to medium-size vessels. Several investigators have compared the ACR and Chapel Hill criteria. [23] In 2022, American College of Rheumatology and the European Alliance of Associations for Rheumatology updated the classification criteria for GPA. [24]
The median annual list price for a new drug was $300,000 in 2023, according to the Reuters analysis of 47 medicines, up from $222,000 a year earlier. ... model by selling a medication in a widely ...
Cutaneous small-vessel vasculitis (CSVV) is inflammation of small blood vessels, usually accompanied by small lumps beneath the skin. [1]: 831 [2] The condition is also known as hypersensitivity vasculitis, cutaneous leukocytoclastic vasculitis, hypersensitivity angiitis, cutaneous leukocytoclastic angiitis, cutaneous necrotizing vasculitis and cutaneous necrotizing venulitis, [3]