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Mucositis is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer. [1] Mucositis can occur anywhere along the gastrointestinal (GI) tract, but oral mucositis refers to the particular inflammation and ulceration that occurs ...
Caphosol has also been associated with low occurrence and severity of oral mucositis in a registry of cancer patients. [3] The registry data provide further evidence to support the use of Caphosol to treat oral mucositis and suggest that Caphosol is associated with a low occurrence and severity of oral mucositis with high adherence to treatment as well as high levels of satisfaction from both ...
Cisplatin and gemcitabine treatment may be associated with less severe side effects. [5] Up to half of people with bladder cancer are not able to take these chemotherapy treatments due to their overall health. Taxanes or vinflunine have been used as second-line therapy (after progression on a platinum containing chemotherapy). [16]
Chemo may also be used in more advanced cases to control the symptoms and side effects of the cancer. [1] After surgery to remove the tumor, a single dose of chemotherapy injected into the bladder is helpful in reducing the rate of cancer recurrence in people who have cancer of the inner lining of the bladder (upper tract urothelial carcinoma ...
Chemo-protective agents have only recently been introduced as a factor involved with chemotherapy with the intent to assist those cancer patients that require treatment, which as an result, improves the patients' quality of life. Amifostine; A common chemo-protective agent that has been approved by the FDA. Examples [2] include:
A partial cystectomy involves removal of only a portion of the bladder and is performed for some benign and malignant tumors localized to the bladder. [9] Individuals that may be candidates for partial cystectomy include those with single tumors located near the dome, or top, of the bladder, tumors that do not invade the muscle of the bladder, tumors located within bladder diverticulum, or ...
It is now well known that a single instillation of this agent within 6 hours of bladder tumor resection can prevent recurrence. The second is in eye surgery where mitomycin C 0.02% is applied topically to prevent scarring during glaucoma filtering surgery and to prevent haze after PRK or LASIK ; mitomycin C has also been shown to reduce ...
Standard chemotherapy regimens are usually administered every 3 weeks to allow normal cells time to recover. This practice has led scientists to the hypothesis that the recurrence of cancer after surgery and chemo may be due to the rapidly diving cells outpacing the rate of chemotherapy administration.