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  2. Mutation - Wikipedia

    en.wikipedia.org/wiki/Mutation

    In genetics, it is sometimes useful to classify mutations as either harmful or beneficial (or neutral): A harmful, or deleterious, mutation decreases the fitness of the organism. Many, but not all mutations in essential genes are harmful (if a mutation does not change the amino acid sequence in an essential protein, it is harmless in most cases ...

  3. Evolution of ageing - Wikipedia

    en.wikipedia.org/wiki/Evolution_of_ageing

    Mutations happen, and they are completely random with respect to a need in the environment and fitness. Mutations can either be beneficial in which they increase an organism's fitness, neutral in which they do not affect an organism's fitness or deleterious where they negatively affect an organism's fitness.

  4. Modifications (genetics) - Wikipedia

    en.wikipedia.org/wiki/Modifications_(genetics)

    There are several methods, or forms, of mutation that exist including spontaneous mutation, errors during replication and repair, as well as mutation due to environmental effects. [8] These origins of mutations can cause many different types of mutations which influence gene expression on both large and small scales.

  5. Mutagenesis - Wikipedia

    en.wikipedia.org/wiki/Mutagenesis

    In nature, the mutations that arise may be beneficial or deleterious—this is the driving force of evolution. An organism may acquire new traits through genetic mutation, but mutation may also result in impaired function of the genes and, in severe cases, causes the death of the organism.

  6. Point mutation - Wikipedia

    en.wikipedia.org/wiki/Point_mutation

    Point germline mutations can lead to beneficial as well as harmful traits or diseases. This leads to adaptations based on the environment where the organism lives. An advantageous mutation can create an advantage for that organism and lead to the trait's being passed down from generation to generation, improving and benefiting the entire ...

  7. Neutral mutation - Wikipedia

    en.wikipedia.org/wiki/Neutral_mutation

    Neutral mutations are changes in DNA sequence that are neither beneficial nor detrimental to the ability of an organism to survive and reproduce. In population genetics , mutations in which natural selection does not affect the spread of the mutation in a species are termed neutral mutations.

  8. Neutral theory of molecular evolution - Wikipedia

    en.wikipedia.org/wiki/Neutral_theory_of...

    The neutral theory assumes that most mutations that are not deleterious are neutral rather than beneficial. Because only a fraction of gametes are sampled in each generation of a species, the neutral theory suggests that a mutant allele can arise within a population and reach fixation by chance, rather than by selective advantage.

  9. Mutational meltdown - Wikipedia

    en.wikipedia.org/wiki/Mutational_meltdown

    In asexual species, the effects of mutation accumulation are more significant compared to sexual species.In an asexual population, all the individual species are equally affected by the selective pressures from the environment, which includes, deleterious and/or beneficial mutations.