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They occur in the parotoid glands, skin, and poison of many toads (Bufonidae family) and other amphibians, and in some plants and mushrooms. [ 1 ] [ 2 ] [ 3 ] The exact composition varies greatly with the specific source of the toxin.
The parotoid gland (alternatively, paratoid gland) is an external skin gland on the back, neck, and shoulder of some frogs (especially toads), and salamanders. It can secrete a number of milky alkaloid substances (depending on the species) known collectively as bufotoxins , which act as neurotoxins to deter predation .
The use of chan'su and love stone (a related toad skin preparation used as an aphrodisiac in the West Indies) has resulted in several cases of poisoning and at least one death. [24] [28] The practice of orally ingesting toad poison has been referred to in popular culture and in the scientific literature as toad licking and has drawn media ...
An example of poison ingestion derives from the poison dart frog. They get a deadly chemical called lipophilic alkaloid from consuming a poisonous food in the rainforest . They are immune to the poison and they secrete it through their skin as a defense mechanism against predators.
The toad's primary defense system is glands that produce a poison that may be potent enough to kill a grown dog. [12] These parotoid glands also produce 5-methoxy-dimethyltryptamine (5-MeO-DMT) [13] and bufotenin (which is named after the Bufo genus of toads); both of these chemicals belong to the family of hallucinogenic tryptamines. Bufotenin ...
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The toad defends itself with a toxin found on its skin. The toxin is released from the parotoid glands which can be identified as pale spots found towards the head. The main component found in the venom is called bufotoxin. All of the venom found on the toad's skin is enough to cause serious symptoms or even death in the attacker.
The cane toad has poison glands, and the tadpoles are highly toxic to most animals if ingested. Its toxic skin can kill many animals, both wild and domesticated, and cane toads are particularly dangerous to dogs.