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5 Alternative methods for reducing acid production. ... famotidine, and nizatidine—are available over the counter in relatively low doses. ...
Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease , gastroesophageal reflux disease , and Zollinger-Ellison syndrome . [ 4 ]
[20] [21] [22] In the United States, the Food and Drug Administration (FDA) has advised that over-the-counter PPIs, such as Prilosec OTC, should be used no more than three 14-day treatment courses over one year. [23] [24] Despite their extensive use, the quality of the evidence supporting their use in some of these conditions is variable.
Chewable tablets are one of the most common forms of antacids, most frequently made from carbonate or hydroxide salts, and are readily available over the counter. Upon reaching the stomach, the powdered antacid salts bind to hydronium (H +) ions, producing chloride salts, carbon dioxide, and water.
Over-the-counter (OTC) medicines at FamilyDoctor.org, maintained by the American Academy of Family Physicians. Contains extensive information on over-the-counter drugs and their responsible use, including specific guidance on several drug classes in question-and-answer format and information on common drug interactions.
In some cases, a person with GERD symptoms can manage them by taking over-the-counter drugs. [50] [51] [52] This is often safer and less expensive than taking prescription drugs. [50] Some guidelines recommend trying to treat symptoms with an H 2 antagonist before using a proton-pump inhibitor because of cost and safety concerns. [50]
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