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The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. The targeted therapy revolution has arrived, but many of the principles and limitations of chemotherapy discovered by the early researchers still apply.
1942 – First chemotherapy drug mustine used to treat cancer [11] 1947 – American Dr. Sidney Farber induces brief remission in a patient with leukaemia with the antifolate drug aminopterin (methotrexate) [4] 1949 – US FDA approves mechlorethamine, a nitrogen mustard compound, for treatment of cancer [12]
The first cause of cancer was identified by British surgeon Percivall Pott, who discovered in 1775 that cancer of the scrotum was a common disease among chimney sweeps. [ citation needed ] The work of other individual physicians led to various insights, but when physicians started working together they could draw firmer conclusions.
There are a number of strategies in the administration of chemotherapeutic drugs used today. Chemotherapy may be given with a curative intent or it may aim to prolong life or to palliate symptoms. Induction chemotherapy is the first line treatment of cancer with a chemotherapeutic drug. This type of chemotherapy is used for curative intent.
Her cancer treatment at Cleveland Clinic started soon after that; it involved having a double mastectomy, as well as several rounds of chemotherapy and radiation.
(Reuters) -The U.S. Food and Drug Administration on Tuesday approved Johnson & Johnson's chemotherapy-free combination treatment for a type of non-small cell lung cancer, setting up a challenge ...
Her first course of treatment involved 35 sessions of radiation, Monday through Friday, for seven weeks, alongside weekly chemotherapy. "The radiation treated my entire mouth, neck and lymph nodes ...
Louis Sanford Goodman (August 27, 1906 – November 19, 2000) was an American pharmacologist. He is best known for his collaborations with Alfred Gilman, Sr., with whom he authored the popular textbook The Pharmacological Basis of Therapeutics in 1941 and pioneered the first chemotherapy trials using nitrogen mustard.