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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Polio is an infection caused by a virus that mostly affects children under 5. ... polio was among the most feared diseases. An explosive 1916 outbreak in New York killed more than 2,000 people and ...
The protein has several domains of which domain D1 contains the polio virus binding site. Within this domain, 37 amino acids are responsible for binding the virus. Poliovirus is an enterovirus. Infection occurs via the fecal–oral route, meaning that one ingests the virus and viral replication occurs in the gastrointestinal tract. [42]
Actress who survived a polio infection she caught as an adult. [13] Tim Rooney: 1947–2006 Actor and voice actor Tim Rooney was the second son of actor Mickey Rooney. He contracted polio as a child and was paralysed for two years. [14] Gianni Russo: born 1943: Actor who played Carlo Rizzi in the 1972 movie The Godfather. He contracted polio at ...
Even people with mild infections can experience post-polio syndrome (PPS) decades later. Symptoms of this non-contagious disease include joint pain, muscle weakness, and mental and physical fatigue.
Despite eradication in recent years, the polio virus is a deadly illness which wreaked havoc in the UK in the 1950s. Scientists have now discovered polio in several sewage samples collected from ...
Young people with polio receiving physiotherapy in the 1950s. The social history of viruses describes the influence of viruses and viral infections on human history. Epidemics caused by viruses began when human behaviour changed during the Neolithic period, around 12,000 years ago, when humans developed more densely populated agricultural communities.
In 1949, John F. Enders (1897–1985) Thomas Weller (1915–2008), and Frederick Robbins (1916–2003) grew polio virus for the first time in cultured human embryo cells, the first virus to be grown without using solid animal tissue or eggs. Infections by poliovirus most often cause the mildest of symptoms.