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  2. Seasonal affective disorder - Wikipedia

    en.wikipedia.org/wiki/Seasonal_affective_disorder

    Seasonal affective disorder (SAD) is a mood disorder subset in which people who typically have normal mental health throughout most of the year exhibit depressive symptoms at the same time each year. [ 1 ] [ 2 ] It is commonly, but not always, associated with the reductions or increases in total daily sunlight hours that occur during the winter ...

  3. Salla disease - Wikipedia

    en.wikipedia.org/wiki/Salla_disease

    Salla disease (SD) or mild Free Sialic Acid Storage Disease (FSASD) is an autosomal recessive [2] lysosomal storage disease characterized by early physical impairment and intellectual disability. Salla disease (also referred to as Finnish-type sialuria , OMIM#604369) was first reported as a lysosomal storage disorder in a family from northern ...

  4. Sudden arrhythmic death syndrome - Wikipedia

    en.wikipedia.org/wiki/Sudden_arrhythmic_death...

    Sudden death of a young person can be caused by heart disease (including cardiomyopathy, congenital heart disease, myocarditis, genetic connective tissue disorders) or conduction disease (WPW syndrome, etc.), medication-related causes or other causes. [13]

  5. Adenylosuccinate lyase deficiency - Wikipedia

    en.wikipedia.org/wiki/Adenylosuccinate_lyase...

    Adenylosuccinate lyase deficiency is responsible for a range of symptoms that involve psychomotor retardation, often accompanied by epileptic seizures, and autistic features. Two common theories were proposed to account for these effects, the first is that they result from decreased concentrations of purine nucleotides needed for purine ...

  6. Dopamine-responsive dystonia - Wikipedia

    en.wikipedia.org/wiki/Dopamine-responsive_dystonia

    Yet some people with dopamine-responsive dystonia do not experience such diurnal fluctuations, causing many researchers to prefer other disease terms. Other symptoms - footwear. excessive wear at toes, but little wear on heels, thus replacement of shoes every college term/semester. Other symptoms - handwriting

  7. Cerebellar ataxia, neuropathy, vestibular areflexia syndrome

    en.wikipedia.org/wiki/Cerebellar_ataxia...

    Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is an autosomal recessive late-onset heredodegenerative multisystem neurological disease. The symptoms include poor balance and difficulty walking. Chronic cough and difficulty swallowing may also be present.

  8. Friedreich's ataxia - Wikipedia

    en.wikipedia.org/wiki/Friedreich's_ataxia

    The disease evolves differently in different people. [36] In general, those diagnosed at a younger age or with longer GAA triplet expansions tend to have more severe symptoms. [5] Congestive heart failure and abnormal heart rhythms are the leading causes of death, [38] but people with fewer symptoms can live into their 60s or older. [22]

  9. 9q34.3 deletion syndrome - Wikipedia

    en.wikipedia.org/wiki/9q34.3_deletion_syndrome

    Kleefstra syndrome affects males and females equally and approximately 75% of all documented cases are caused by Eu-HMTase1 disruptions while only 25% are caused by 9q34.3 deletions. [3] There are no statistics on the effect the disease has on life expectancy due to the lack of information available. [3]