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Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; [1] this may be measured by echocardiography or cardiac catheterization.
Diagram of a pulmonary artery catheter in position. The pulmonary wedge pressure (PWP) (also called pulmonary arterial wedge pressure (PAWP), pulmonary capillary wedge pressure (PCWP), pulmonary artery occlusion pressure (PAOP), or cross-sectional pressure) is the pressure measured by wedging a pulmonary artery catheter with an inflated balloon into a small pulmonary arterial branch. [1]
Elevated white blood cell count may suggest a non-cardiogenic cause such as sepsis or infection. [12] B-type natriuretic peptide (BNP) is available in many hospitals, sometimes even as a point-of-care test. Low levels of BNP (<100 pg/ml) suggest a cardiac cause is unlikely, and suggest noncardiogenic pulmonary edema. [3]
There is a circulatory overload which may lead to pulmonary edema secondary to an elevated diastolic pressure in the left ventricle. These individuals usually have a normal systolic function but symptoms are those of heart failure. With time, this overload causes systolic failure. Ultimately cardiac output can be reduced to very low levels. [1]
Coronary Vasculature. Coronary perfusion pressure (CPP) refers to the pressure gradient that drives coronary blood pressure.The heart's function is to perfuse blood to the body; however, the heart's own myocardium (heart muscle) must, itself, be supplied for its own muscle function.
[10] [11] The WHO classification system in 2022 (with adaptations from the more recent ESC/ERS guidelines shown in italics) can be summarized as follows: [4] [11] [12] WHO Group I – Pulmonary arterial hypertension (PAH) Caused by narrowing and thickening of tiny arteries of the lung [13] Idiopathic in most cases (heritable in some cases) [13]
Afterload is the mean tension produced by a chamber of the heart in order to contract. It can also be considered as the ‘load’ that the heart must eject blood against. Afterload is, therefore, a consequence of aortic large vessel compliance, wave reflection, and small vessel resistance (LV afterload) or similar pulmonary artery parameters (RV afterload
To determine the reason behind the elevated serum total protein, a serum protein electrophoresis should be carried out. [2] ... 10.24272/j.issn.2095-8137.2021.397 ...