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An anaphase lag of a chromosome 21 in a Down syndrome embryo leads to a fraction of euploid cells (2n cells), phenomenon described as "aneuploidy rescue". There is considerable variability in the fraction of cells with trisomy 21, both as a whole and tissue-by-tissue. This is the cause of 1–2% of the observed Down syndromes. [4]
Down syndrome or Down's syndrome, [12] also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] It is usually associated with developmental delays, mild to moderate intellectual disability , and characteristic physical features.
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Modified version of Image:Autosomal Dominant Pedigree Chart.svg. Enlarged letters, cropped. Its description is: Autosomal Dominant Pedigree Chart. In Autosomal Dominance the chance of receiving and expressing a particular gene is 50% regardless of the sex of parent or child. Date: 2006-07-22, modified 2008-05-24: Source
Autosomal dominant pedigree chart. In Autosomal Dominance the chance of receiving and expressing a particular gene is 50% regardless of the sex of parent or child. Date: 22 July 2006: Source: Own work: Author: Jerome Walker: Permission (Reusing this file)
Freebird is a 2021 Canadian 2D animated short film written and directed by Michael Joseph McDonald and Joe Bluhm, and co-led by creative director Nicholas Herd. [1] The plot follows Jon, a boy with Down syndrome, navigating the world with a loving mother, an absent father, and a life-long crush.
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